Performing Hong-Ou-Mandel-type numerical experiments with repulsive condensates: the case of dark and dark-bright solitons

The Hong-Ou-Mandel experiment leads indistinguishable photons simultaneously reaching a 50:50 beam splitter to emerge on the same port through a two-photon interference. Motivated by this phenomenon, we consider numerical experiments of the same flavor for classical wave objects in the setting of repulsive condensates. We examine dark solitons interactingwith a repulsive barrier, a case inwhich we find no significant asymmetries in the emerging waves after the collision, presumably due to their topological nature. We also consider case examples of two-component systems, where the dark solitons trap a bright structure in the second component (dark-bright solitary waves). For these, pronounced asymmetries upon collision are possible for the nontopological bright component. We also show an example of a similar phenomenology for ring dark-bright structures in two dimensions

Orbital Josephson effect and interactions in driven atom condensates on a ring

In a system of ac-driven condensed bosons we study a new type of Josephson effect occurring between states sharing the same region of space and the same internal atom structure. We first develop a technique to calculate the long time dynamics of a driven interacting many-body system. For resonant frequencies, this dynamics can be shown to derive from an effective time-independent Hamiltonian which is expressed in terms of standard creation and annihilation operators. Within the subspace of resonant states, and if the undriven states are plane waves, a locally repulsive interaction between bosons translates into an effective attraction. We apply the method to study the effect of interactions on the coherent ratchet current of an asymmetrically driven boson system. We find a wealth of dynamical regimes which includes Rabi oscillations, self-trapping, and chaotic behavior. In the latter case, a full many-body calculation deviates from the mean-field results by predicting large quantum fluctuations of the relative particle number.Comment: Published versio

Interactions of solitons with a Gaussian barrier: splitting and recombination in quasi-one-dimensional and three-dimensional settings

The interaction of matter–wave solitons with a potential barrier is a fundamentally important problem, and the splitting and subsequent recombination of the soliton by the barrier is the essence of soliton matter–wave interferometry. We demonstrate the three-dimensional (3D) character of the interactions in the case relevant to ongoing experiments, where the number of atoms in the soliton is relatively close to the collapse threshold. We examine the soliton dynamics in the framework of the effectively one-dimensional (1D) nonpolynomial Schr¨odinger equation (NPSE), which admits the collapse in a modified form, and in parallel we use the full 3D Gross–Pitaevskii equation (GPE). Both approaches produce similar results, which are, however, quite different from those produced in recent work that used the 1D cubic GPE. Basic features, produced by the NPSE and the 3D GPE alike, include (a) an increase in the first reflection coefficient for increasing barrier height and decreasing atom number; (b) large variation of the secondary reflection/recombination probability versus barrier height; (c) pronounced asymmetry in the oscillation amplitudes of the transmitted and reflected fragments; and (d) enhancement of the transverse excitations as the number of atoms is increased. We also explore effects produced by variations of the barrier width and outcomes of the secondary collision upon phase imprinting on the fragment in one arm of the interferometer

Short-term safety evaluation of processed calcium montmorillonite clay (NovaSil) in humans

Abstract NovaSil clay (NS) provides significant protection from the adverse effects of aflatoxins (AFs) in multiple animal species by decreasing bioavailability from the gastrointestinal tract. It is postulated that NS clay can be safely added to human diets to diminish exposure and health risks from AF contaminated food. To determine the safety and tolerance of NS in humans and establish dosimetry protocols for long-term efficacy studies, a randomized and double-blinded phase I clinical trial was conducted. Volunteers (20-45 yr in age), were clinically screened for confirmation of their health status. Fifty subjects (23 males and 27 females) were randomly divided into two groups: The low-dose group received nine capsules containing 1.5 g/day, and the high-dose group received nine capsules containing 3.0 g/day for a period of 2 wk. NS capsules were manufactured in the same color and size and were distributed to each participant three times a day at designated sites where follow-up was taken to record any side effects and complaints. Blood and urine samples were collected before and after the study for laboratory analysis. All participants completed the trial and compliance was 99.1%. Mild GI effects were reported in some participants. Symptoms included abdominal pain (6%, 3/50), bloating (4%, 2/50), constipation (2%, 1/50), diarrhea (2%, 1/50), and flatulence (8%, 4/50). No statistical significance was found between the two groups for these adverse effects ( p > 0.25). No significant differences were shown in hematology, liver and kidney function, electrolytes, vitamins A and E, and minerals in either group. These results demonstrate the relative safety of NS clay in human subjects and will serve as a basis for long-term human trials in populations at high risk for aflatoxicosis

Neonatal CD8 T-cell Hierarchy Is Distinct from Adults and Is Influenced by Intrinsic T cell Properties in Respiratory Syncytial Virus Infected Mice

Following respiratory syncytial virus infection of adult CB6F1 hybrid mice, a predictable CD8+ T cell epitope hierarchy is established with a strongly dominant response to a Kd-restricted peptide (SYIGSINNI) from the M2 protein. The response to KdM282-90 is ∼5-fold higher than the response to a subdominant epitope from the M protein (NAITNAKII, DbM187-195). After infection of neonatal mice, a distinctly different epitope hierarchy emerges with codominant responses to KdM282-90 and DbM187-195. Adoptive transfer of naïve CD8+ T cells from adults into congenic neonates prior to infection indicates that intrinsic CD8+ T cell factors contribute to age-related differences in hierarchy. Epitope-specific precursor frequency differs between adults and neonates and influences, but does not predict the hierarchy following infection. Additionally, dominance of KdM282-90 –specific cells does not correlate with TdT activity. Epitope-specific Vβ repertoire usage is more restricted and functional avidity is lower in neonatal mice. The neonatal pattern of codominance changes after infection at 10 days of age, and rapidly shifts to the adult pattern of extreme KdM282- 90 -dominance. Thus, the functional properties of T cells are selectively modified by developmental factors in an epitope-specific and age-dependent manner